Tissue Elasticity Regulated Tumor Gene Expression: Implication for Diagnostic Biomarkers of Primitive Neuroectodermal Tumor
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منابع مشابه
Tissue Elasticity Regulated Tumor Gene Expression: Implication for Diagnostic Biomarkers of Primitive Neuroectodermal Tumor
BACKGROUND The tumor microenvironment consists of both physical and chemical factors. Tissue elasticity is one physical factor contributing to the microenvironment of tumor cells. To test the importance of tissue elasticity in cell culture, primitive neuroectodermal tumor (PNET) stem cells were cultured on soft polyacrylamide (PAA) hydrogel plates that mimics the elasticity of brain tissue comp...
متن کاملCorrection: Tissue Elasticity Regulated Tumor Gene Expression: Implication for Diagnostic Biomarkers of Primitive Neuroectodermal Tumor
There are errors in the Funding Section. The correct Funding is as follows: This study was supported by the Children's Hospital of Orange County (CHOC) Children's Foundation, CHOC Neuroscience Institute, Austin Ford Tribute Fund, W. M. Keck Foundation, Grants R01CA164509 (National Institutes of Health), CHE-1213161 (National Science Foundation), and a Seed Grant from University of Southern Cali...
متن کاملPeripheral Primitive Neuroectodermal Tumor of the Pelvis
The primitive neuroectodermal tumor (PNET) belongs to a group of highly malignant tumors and is composed of small round cells of a neuroectodermal origin. Categorized in the same tumor family as Ewing sarcoma, the PNET is most likely to occur in bones and soft tissues. However, a small number of PNET cases arising in the pelvis have been reported as well. We present three cases of pelvic PNET: ...
متن کاملPrimitive Neuroectodermal Tumor of the Kidney
Primitive neuroectodermal tumor (PENETs) is an uncommon malignancy of bone and soft tissue witch rarely occurs in the kidney. In more than 90% of the cases, the tumor cells relieves a balanced translocation (11; 22) (q24; q12). Immunohistochemical staining may be required for diagnosis of PENET. The cells of tumor express CD99, vimentin, NSE, FL1 but do not express Ck, LCA, myogenin, and WT1. W...
متن کاملCongenital Primitive Neuroectodermal Tumor (PNET) of the Orbit
Purpose: To report a case of the congenital primitive neuroectodermal tumor (PNET) of the orbit. Case Report: The patient was a 2-week-old neonate referred to the oculoplastic clinic with right eye proptosis from birth. The neonate was a full term with a history of difficult vaginal delivery. At an initial examination, the ecchymosis of the medial right upper lid was noted. At an initial CT sca...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2015
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0120336